Mrs. Cunningham is Randy's mother, but she has only been mentioned in a few episodes.
- Randy had to shop for two hours with her in order to get McFistios, according to the description in "McFists of Fury".
- When trying to call Howard in "Weinerman Up", Randy uses the voice command on his cellphone, which only results in it calling Mom.
- Howard gives Randy half of the chess trophy in "Stanks Like Teen Spirit", and as they walk away, Randy points out that his parents would only be half as proud.
- In "Swampy Seconds", Randy says that his mother thought the hours he played Swamp Puncher would add up to nothing as he drives a fan-boat.
- When Randy pretends to be sick in "Randy Cunningham's Day Off", he calls for her, complaining about how bad he feels and not wanting to go to school.
- Like Viceroy, Randy's mom has been mentioned, but besides saying he had parents once, Randy's father has never been mentioned.
- Probably as a joke, a video for rap contest between Phineas and Ferb and Randy Cunningham: 9th Grade Ninja for Disney XD ZA, a picture of Randy's mom appears, pretty much a modified image of Randy dressed up like a mother.